Protein Purification Reagents and Kits
Cayman Chemical S-Acetyl-L-glutathIon 25g
A derivative of glutathione; more stable in plasma than GSH; converted to GSH by intracellular thioesterases; increases intracellular GSH levels in primary fibroblasts derived from patients with glutathione synthetase deficiency at 50 μM; induces apoptosis in Daudi, Raji, and Jurkat lymphoma cells at 5 mM; inhibits the replication of HSV-1 in human foreskin fibroblasts at 5 and 10 mM; increases survival in a mouse model of HSV-1 infection at 6.25 μg/g per day
Medchemexpress LLC RAS/RAS-RAF-IN-1 | 2447039-81-6 | 99.8% | 807.98 | 1 ML
RAS/RAS-RAF-IN-1 is a potent inhibitor of both RAS and RAS-RAF pathways. It demonstrates a KD of 5.0 μM-15 μM for cyclophilin A (CYPA) binding affinity and exhibits antitumor activity.
- Potent inhibitor of Ras and Raf.
- Exhibits antitumor activity.
- EC50 of 0.5 μM-5.0 μM for BRAF-GTP-KRAS-G12C disruption.
- IC50 of 1.0 μM-10 μM for pERK inhibition in H358 cells.
AdipoGen VISTA msCOMP msrecHis
Protein. The extracellular domain of mouse VISTA aa 33-191 is fused at the C-terminus to the domain of the mouse cartilage oligomeric matrix protein COMP aa 28-72 and a His Tag. Source HEK 293 cells. Endotoxin content <0.01EU/µg purified protein LAL test Lonza. Lyophilized. Contains PBS. Purity >95% SDS-PAGE. Mouse VISTA is a 55 to 65kDa type I Ig membrane protein with the extracellular domain homologous to PD-L1. VISTA is mainly expressed on hematopoietic tissues spleen, thymus and bone marrow and on myeloid cells with lower expression on CD4 and CD8 T cells. VISTA is a new negative checkpoint regulator that potently suppresses T cell activation. Overexpression of VISTA on tumors inhibits the protective anti-tumor immunity and blockade of VISTA enhances antitumor immunity in multiple tumor models. VISTA on APC delivers negative signaling to T cells via a yet-to-identify binding partner on T cells.
American Research Products Inc Rat a glutathione S transferas
Rat a-glutathione S-transferases a-GST ELISA Kit from CUSABIO Detection Range 0 156 mU/mL-10 mU/mL Sensitivity 0 039 mU/mL Sample serum plasma tissue homogenates cell lysates Method Sandwich
Miltenyi Biotec, Inc. MACS GMP CD45RA-FITC
GMP grade antibody for identification of CD45RA positive cells by flow cytometry as well as cell enrichment by flow cytometric sorting.
This product is subject to the following: Miltenyi Biotec, Inc. Terms and Conditions of Sale For Products and Services
Cayman Chemical DL-Sulforaphn GlutathIon 10mg
A metabolite of sulforaphane; increases mRNA expression of GSTA1 and UGT1A1 in HepG2 cells at 15 µM
ABclonal Technology Glutathione Peroxidase 2
The protein encoded by this gene is a member of the glutathione peroxidase family which reduces organic hydroperoxides and hydrogen peroxide (H2O2) using glutathione to protect against oxidative damage This isozyme is primarily expressed in the gastrointestinal tract and liver localized in the cytoplasm and prefers hydrogen peroxide as a substrate Overexpression is linked to increased differentiation and proliferation in colorectal cancer As a selenoprotein it contains selenocysteine (Sec) at its active site encoded by the UGA codon The 3 UTR of selenoprotein mRNAs has a Sec insertion sequence (SECIS) element enabling UGA to code for Sec instead of terminating translation Alternative splicing results in different transcript variants
Genscript Corporation Glutathione MagBeads
The GenScript Glutathione MagBeads are developed for quick and efficient small scale purification of recombinant glutathione S transferase (GST)-tagged fusion proteins from bacteria yeast and mammalian crude cell lysates
Cayman Chemical GST GlutathIon 1ea
An NQO1 substrate and a derivative ofBlapachone converted by NQO1 to NAD and increases the ratio of NAD to NADH in a cell-free assay as well as C2C12 and L6 myoblasts at 1 1 or 2 UM respectively increases intracellular ATP levels as well as decreases intracellular lactate and ROS levels in primary fibroblasts isolated from patients with MELAS at 1 UM increases the levels of mitochondrial complex I and mitochondrial complex III as well as increases the OCR in primary fibroblasts isolated from patients with MELAS at 1 UM inhibits cisplatin-induced apoptosis production of mitochondrial ROS and mitochondrial membrane depolarization in primary mouse cochlear organ of Corti cells at 1 UM
Cayman Chemical DL-Sulforaphn GlutathIon 5mg
A metabolite of sulforaphane; increases mRNA expression of GSTA1 and UGT1A1 in HepG2 cells at 15 µM
American Research Products Inc Human Glutathione S transferas
Human Glutathione S-transferase omega-1 (GSTO1) ELISA kit from CUSABIO Detection Range 31 2 pg/mL-2000 pg/mL Sensitivity 7 8 pg/mL Sample serum plasma tissue homogenates cell lysates Method Sandwich
ABclonal Technology Phospho-B-Raf-S445 Rabbit pAb
This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene, most commonly the V600E mutation, are the most frequently identified cancer-causing mutations in melanoma, and have been identified in various other cancers as well, including non-Hodgkin lymphoma, colorectal cancer, thyroid carcinoma, non-small cell lung carcinoma, hairy cell leukemia and adenocarcinoma of lung. Mutations in this gene are also associated with cardiofaciocutaneous, Noonan, and Costello syndromes, which exhibit overlapping phenotypes. A pseudogene of this gene has been identified on the X chromosome.
American Research Products Inc Mouse Eosinophil PeroXidase E
Mouse Eosinophil PeroXidase (EPO) ELISA Kit from CUSABIO Detection Range 0 156 ng/mL-10 ng/mL Sensitivity 0 039 ng/mL Sample serum plasma tissue homogenates Method Sandwich